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[使用99锝亚甲基二膦酸盐(MDP)和67镓进行感染性骨关节炎病理的同步闪烁扫描探索。初步结果]

[Simultaneous scintigraphy exploration using MDP - 99 Tc and 67GA in infectious osteoarticular pathology. Initial results].

作者信息

Steinling M, Coequyt S, Marchandise X, Beuscart R, Vergnes R

出版信息

Rev Rhum Mal Osteoartic. 1982 Jul-Sep;49(8-9):635-41.

PMID:6227076
Abstract

A new investigation in infectious osteoarticular pathology is presented, involving the use of two tracers: one for bone metabolism (MDP - 99mTc), the other for the infectious process (67Ga). The initial results of a prospective study of 72 scintigraphic examinations are reported. Analysis of the results reveals the value in using 67Ga to determine the stage of development of the lesion and consequently to adapt the treatment. Classical bone scintigraphy, whose value remains the early detection of signs compared to radiography, does not allow us to follow the course of the lesion over time. The need to combine scintigraphic techniques has already been recognised (Lisbona, Gaucher) but there has usually been sequential meaning, apart from the risk of false negatives (early osteitis), repeated visits by the patients over a period of time. The simultaneous use of 2 tracers, technically possible, avoids these problems and produces a rapid result (generally 6 hours after the injection).

摘要

本文介绍了一项关于感染性骨关节炎病理学的新研究,该研究使用了两种示踪剂:一种用于骨代谢(99mTc-MDP),另一种用于感染过程(67Ga)。报告了一项对72次骨闪烁显像检查的前瞻性研究的初步结果。结果分析显示,使用67Ga确定病变发展阶段并据此调整治疗具有重要价值。经典骨闪烁显像与放射摄影相比,其价值在于早期发现体征,但无法让我们随时间跟踪病变进程。联合使用闪烁显像技术的必要性已得到认可(利斯博纳、戈谢),但通常是按顺序使用,除了存在假阴性风险(早期骨炎)外,患者还需要在一段时间内多次就诊。同时使用两种示踪剂在技术上是可行的,可避免这些问题并能快速得出结果(一般在注射后6小时)。

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