Fiorini G, Monarca A, Adelasco L, Croce G, Natangelo R, Gibelli A
Biomed Pharmacother. 1983;37(4):180-3.
The correlation between serum immunoglobulin levels and "helper/suppressor" (T4/T8) ratio has been investigated in 45 patients with biopsy proven liver diseases (22 with ALD, 16 with CAH and 7 with VHR). In the ALD and CAH groups the T4/T8 ratio was significantly higher than in normal controls and a strong correlation was noticed with IgA, but not IgG and IgM levels. The same correlation was found in the VHR group as well, even if the mean value for the T4/T8 ratio in these patients was not significantly above that of normal controls. The pathogenetic significance of these findings is discussed.
对45例经活检证实患有肝病的患者（22例酒精性肝病、16例慢性活动性肝炎和7例病毒相关性肝炎）的血清免疫球蛋白水平与“辅助/抑制”（T4/T8）比值之间的相关性进行了研究。在酒精性肝病和慢性活动性肝炎组中，T4/T8比值显著高于正常对照组，并且发现与IgA水平有很强的相关性，但与IgG和IgM水平无关。在病毒相关性肝炎组中也发现了同样的相关性，即使这些患者的T4/T8比值平均值并未显著高于正常对照组。讨论了这些发现的发病学意义。
