Simon P, Ang K S, Bavay P, Cloup C, Mignard J P, Ramee M P
Presse Med. 1984 Feb 11;13(5):257-60.
Between April 1, 1975 and May 1, 1982, 192 cases of primary glomerulonephritis were histologically diagnosed in the Nephrology centre of a health district with 250 000 inhabitants; 58 (30.2%) of the lesions were IgA glomerulonephritis. All patients were born and lived in that district. At the end of the period under review the prevalence of IgA glomerulonephritis was evaluated at 1/10 000 and its incidence at 2.5/100 000 per year. The disease began in subjects under 35 years of age in 65% of the cases, with a peak between 16 and 25 years. Thirty-seven patients were symptom-free, and the condition was diagnosed either at recruitment in the army (15 cases; 25.2%) or during the annual medical examination of industrial workers (19 cases; 39.7%). At the end of the study, 21 patients (36%) had renal failure, and 5 of these (8.5%) were under periodical haemodialysis. This study shows how valuable it would be from a socio-economic point of view if the role played by public health institutions in detecting the disease were confirmed and if its prevalence among the French population were precisely known.
1975年4月1日至1982年5月1日期间，在一个拥有25万居民的健康区的肾脏病中心，经组织学诊断出192例原发性肾小球肾炎；其中58例（30.2%）病变为IgA肾病。所有患者均在该地区出生并居住。在审查期结束时，IgA肾病的患病率评估为万分之一，年发病率为十万分之二点五。65%的病例发病年龄在35岁以下，发病高峰在16至25岁之间。37例患者无症状，病情在征兵体检时（15例；25.2%）或产业工人年度体检时（19例；39.7%）被诊断出来。研究结束时，21例患者（36%）出现肾衰竭，其中5例（8.5%）接受定期血液透析。这项研究表明，如果公共卫生机构在疾病检测中的作用得到确认，并且其在法国人群中的患病率能够确切知晓，从社会经济角度来看将具有很大价值。
