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[完整小鼠中淋巴细胞辅助功能与巨噬细胞吞噬活性的关系]

[Lymphocyte helper function in intact mice in relation to macrophage phagocytic activity].

作者信息

Vikhot N E

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1983 Dec(12):73-5.

PMID:6229953
Abstract

The results of the studies aimed at the determination of the presence of lymphocytes, influencing the phagocytic activity of macrophages, among the cells of the peritoneal cavity, the spleen and the thymus in intact CBA mice are presented. Macrophages cultivated together with the nonadhering cells of peritoneal exudate were found to possess greater phagocytic activity in comparison with macrophages free of nonadhering cells. The nonadhering cells and splenocytes were also found to possess helper activity with respect to the phagocytic activity of macrophages: their addition to washed out macrophages increased the phagocytic index. Thymocytes showed no such activity.

摘要

本文展示了旨在确定在未受损伤的CBA小鼠的腹腔、脾脏和胸腺细胞中,影响巨噬细胞吞噬活性的淋巴细胞是否存在的研究结果。与不含非黏附细胞的巨噬细胞相比,与腹腔渗出液中的非黏附细胞共同培养的巨噬细胞具有更强的吞噬活性。还发现非黏附细胞和脾细胞对巨噬细胞的吞噬活性具有辅助作用:将它们添加到洗涤后的巨噬细胞中可提高吞噬指数。胸腺细胞则无此活性。

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