Pollen J J, Witztum K F, Ashburn W L
AJR Am J Roentgenol. 1984 Apr;142(4):773-6. doi: 10.2214/ajr.142.4.773.
The radionuclide bone scan 3 months after the initiation of treatment for advanced cancer of the prostate occasionally shows apparent progression of individual lesions despite clinical improvement. To determine the incidence and clinical significance of this so-called flare phenomenon, serial bone scans were reviewed in 33 patients with carcinoma of the prostate and bony metastases, who were receiving endocrine treatment for the first time. A flare reaction was seen in two (6%) of 33 bone scans obtained 3 months after initiation of treatment. A flare reaction on bone scan is an unusual phenomenon in prostatic cancer; in general, serial scans accurately depict the activity of bony metastases in these patients.
在晚期前列腺癌治疗开始3个月后的放射性核素骨扫描，偶尔会显示尽管临床症状有所改善，但个别病灶却有明显进展。为了确定这种所谓的闪烁现象的发生率及临床意义，我们回顾性分析了33例首次接受内分泌治疗的前列腺癌伴骨转移患者的系列骨扫描结果。在治疗开始3个月后所进行的33次骨扫描中，有2次（6%）出现了闪烁反应。骨扫描出现闪烁反应在前列腺癌中是一种不常见的现象；一般来说，系列扫描能够准确描绘出这些患者骨转移灶的活性。
