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1
Some ethical issues in dementia research.痴呆症研究中的一些伦理问题。
J Med Ethics. 1984 Mar;10(1):29-31. doi: 10.1136/jme.10.1.29.
2
Ethical and social issues in presymptomatic testing for Huntington's disease: a European Community collaborative study. European Community Huntington's Disease Collaborative Study Group.亨廷顿舞蹈症症状前检测中的伦理和社会问题:一项欧洲共同体合作研究。欧洲共同体亨廷顿舞蹈症合作研究小组
J Med Genet. 1993 Dec;30(12):1028-35. doi: 10.1136/jmg.30.12.1028.
3
Confidentiality and Huntington's chorea.保密与亨廷顿舞蹈症
J Med Ethics. 1990 Dec;16(4):196-9. doi: 10.1136/jme.16.4.196.
4
Huntington's disease and the ethics of genetic prediction.亨廷顿舞蹈症与基因预测的伦理问题
J Med Ethics. 1992 Jun;18(2):79-85. doi: 10.1136/jme.18.2.79.
5
Interests, obligations, and justice: some notes toward an ethic of managed care.利益、义务与公正:关于管理式医疗伦理的几点笔记
J Clin Ethics. 1995 Winter;6(4):312-7.
6
[The predictive test in Huntington's chorea and the request not to be informed about results; an ethical problem with implications for the future].
Ned Tijdschr Geneeskd. 1990 Jun 2;134(22):1107-8.
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Brain resuscitation. Ethical perspectives.脑复苏。伦理视角。
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[Ethical dilemmas in early detection of dementia. An inventory of moral intuitions in practice].
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Ethical dilemmas in clinical genetics.临床遗传学中的伦理困境。
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Olfactory bulb alpha-synucleinopathy has high specificity and sensitivity for Lewy body disorders.嗅球α-突触核蛋白病对路易体疾病具有高度的特异性和敏感性。
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本文引用的文献

1
Some ethical problems in Huntington's chorea.亨廷顿舞蹈症中的一些伦理问题。
Can Med Assoc J. 1981 Nov 15;125(10):1098-100.
2
Objective knowledge about Huntington's disease and attitudes towards predictive tests of persons at risk.关于亨廷顿舞蹈症的客观知识以及对有患病风险者进行预测性检测的态度。
J Med Genet. 1981 Feb;18(1):31-9. doi: 10.1136/jmg.18.1.31.
3
Adult dementia: history, biopsy, pathology.成人痴呆:病史、活检、病理学
Neurosurgery. 1979 May;4(5):434-42. doi: 10.1227/00006123-197905000-00011.
4
Attitudes of families to some aspects of Huntington's chorea.家庭对亨廷顿舞蹈症某些方面的态度。
Psychol Med. 1979 May;9(2):327-36. doi: 10.1017/s0033291700030841.
5
Attitudes of patients and their relatives to Huntington's disease.患者及其亲属对亨廷顿病的态度。
J Med Genet. 1975 Sep;12(3):217-23. doi: 10.1136/jmg.12.3.217.

痴呆症研究中的一些伦理问题。

Some ethical issues in dementia research.

作者信息

Mahendra B

出版信息

J Med Ethics. 1984 Mar;10(1):29-31. doi: 10.1136/jme.10.1.29.

DOI:10.1136/jme.10.1.29
PMID:6231378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1374925/
Abstract

The ethical problems associated with dementia have been thrown into focus by the ageing population. The elderly form a disadvantaged group in society and the author wonders if it is morally justified to pursue research into ways of arresting pathology without concomitant attention being paid to the quality of life of the surviving elderly. Precise diagnosis of dementia requires invasive, and potentially injurious, brain biopsy. Recent thinking has pointed to some of the advantages of biopsy. The question of consent in a patient with impaired mental function has to be borne in mind. As for the special ethical problems associated with Huntington's chorea, it is argued there is no justification for withholding information from, or for authoritarian direction of, patients and 'at risk' relatives but the importance of full discussion before undertaking predictive procedures is stressed.

摘要

老龄化人口使与痴呆症相关的伦理问题成为焦点。老年人在社会中构成弱势群体,作者质疑在致力于研究阻止病理过程的方法时,却不关注尚存老年人的生活质量,在道德上是否合理。痴呆症的精确诊断需要进行侵入性的、可能有伤害的脑活检。最近的观点指出了活检的一些优点。必须考虑到精神功能受损患者的同意问题。至于与亨廷顿舞蹈症相关的特殊伦理问题,有人认为,向患者及“有患病风险”的亲属隐瞒信息或进行专制指导是没有道理的,但强调在进行预测性程序之前进行充分讨论的重要性。