Kanemoto N, Hör G, Kober G, Kaltenbach M
Jpn Heart J. 1983 Nov;24(6):891-907. doi: 10.1536/ihj.24.891.
Quantitative evaluation of exercise T1-201 myocardial scintigraphy was carried out to determine the effect of transluminal coronary angioplasty (TCA) in 15 patients with critical coronary artery stenoses (greater than or equal to 70%). Thirteen lesions were successfully dilated (reduction in stenosis by more than 30%); two were unsuccessful. Calculated indices from T1-201 myocardial scintigraphy, using a semi-automatic computer image processing system, included washout factor (WF), vitality index (VI) and redistribution factor (RDF). No changes were noted in WF before and after dilatation. The VI increased in successfully dilated patients from 66.3 +/- 8.5% (mean +/- SD) to 77.8 +/- 10.9% (p less than 0.001) in the areas perfused by the vessels containing the lesions. The RDF decreased significantly after dilatation from 4.4 +/- 6.1% to 1.2 +/- 2.8% (p less than 0.05) 1 hour after exercise and from 10.4 +/- 7.5% to 4.1 +/- 4.2% (p less than 0.01) 3-4 hours after exercise. From these results, we conclude that the perfusion of ischemic areas distal to critical coronary artery stenoses improves following successful dilatation. T1-201 myocardial scintigraphy was shown to be very useful in the evaluation of TCA.
对15例冠状动脉严重狭窄（大于或等于70%）的患者进行了运动T1-201心肌闪烁显像的定量评估，以确定经皮腔内冠状动脉成形术（TCA）的效果。13处病变成功扩张（狭窄程度降低超过30%）；2处未成功。使用半自动计算机图像处理系统从T1-201心肌闪烁显像计算得出的指标包括洗脱因子（WF）、活力指数（VI）和再分布因子（RDF）。扩张前后WF未见变化。在病变血管灌注区域，成功扩张患者的VI从66.3±8.5%（均值±标准差）增至77.8±10.9%（p<0.001）。运动后1小时，RDF在扩张后显著降低，从4.4±6.1%降至1.2±2.8%（p<0.05）；运动后3至4小时，从10.4±7.5%降至4.1±4.2%（p<0.01）。根据这些结果，我们得出结论，冠状动脉严重狭窄远端缺血区域的灌注在成功扩张后得到改善。T1-201心肌闪烁显像在TCA评估中显示非常有用。
