Simonetti G, Rossi P, Passariello R, Pesce B, Rovasio S S, Urigo F, Canalis G C, Tomiselli A
Radiol Med. 1983 Sep;69(9):625-31.
We have treated 56 stenoses of renal arteries in 50 patients in which a renin assay indicated renovascular hypertension. In this paper we refer only to 40 cases of renal arteries angioplasty in 37 patients (3 cases of bilateral stenoses) with a clinical follow-up of 12 months. 25 lesions were of arteriosclerotic nature, while 15 were due to fibromuscular displasia. Results demonstrated that angioplasty resolved hypertensive conditions (either with or without medical therapy) in 82% of the cases of arteriosclerotic lesions and in 86% of the stenoses due to fibromuscular displasia. Although extremely rare, the complications that may occur with this procedure are very serious (arterial rupture, acute thrombosis, peripheral embolization). Out of utmost importance is a close collaboration with a vascular surgeon. Without doubt angioplasty will bring about radical changes in the preparation of therapeutical protocol and in some selected cases to improve renal function.
我们对50例经肾素测定提示肾血管性高血压的患者的56处肾动脉狭窄进行了治疗。本文仅涉及37例患者(3例双侧狭窄)的40例肾动脉血管成形术,临床随访12个月。25处病变为动脉粥样硬化性质,15处为纤维肌性发育异常所致。结果表明,血管成形术使82%的动脉粥样硬化性病变病例以及86%的纤维肌性发育异常所致狭窄病例的高血压状况(无论是否接受药物治疗)得到缓解。尽管这种手术可能出现的并发症极为罕见,但非常严重(动脉破裂、急性血栓形成、外周栓塞)。与血管外科医生密切合作至关重要。毫无疑问,血管成形术将给治疗方案的制定带来根本性变化,并在一些选定病例中改善肾功能。