Grossman J H, Adams R L, Hierholzer W J, Andriole V T
Am J Obstet Gynecol. 1978 Feb 1;130(3):312-6.
The utility of culturing the cut edge of the vaginal cuff and endometrium of the uterine specimens of patients undergoing elective hysterectomy and receiving antibiotic prophylaxis has been critically examined. Subjects for this study represent a randomized subpopulation of patients participating in a larger controlled, prospective, double-blind study of antibiotic prophylaxis which has been conducted at Yale-New Haven Hospital during the past five years. On the basis of the organisms recovered, speculation is raised concerning the existence of an endometrial flora and the mechanisms of postoperative vaginal cuff infection in patients treated and not treated with antibiotic prophylaxis at the time of hysterectomy.
对于接受择期子宫切除术并接受抗生素预防治疗的患者，其子宫标本的阴道断端和子宫内膜进行培养的效用已受到严格审查。本研究的受试者是参与一项更大规模的抗生素预防对照、前瞻性、双盲研究的患者随机亚组，该研究过去五年在耶鲁-纽黑文医院进行。根据分离出的微生物，对子宫内膜菌群的存在以及子宫切除时接受和未接受抗生素预防治疗的患者术后阴道断端感染的机制提出了推测。
