两条大核苷酸链的折叠
Folding of two large nucleotide chains.
作者信息
Nussinov R, Pieczenik G
出版信息
J Theor Biol. 1984 Feb 7;106(3):261-73. doi: 10.1016/0022-5193(84)90030-4.
PMID:6232430
Abstract
We have already described the FOLD-A code designed for folding mRNA's and single stranded DNA molecules (Nussinov & Pieczenik, 1984). In this paper we describe its application to two long polynucleotide chains: the A protein gene of the MS2 RNA and the whole genome of the phi X 174 phage. The folded form of the single stranded DNA of the phi X 174 is a six armed star with the origin of replication in its center.
摘要
我们已经描述了用于折叠信使核糖核酸（mRNA）和单链脱氧核糖核酸（DNA）分子的FOLD-A编码（努西诺夫和皮采尼克，1984年）。在本文中，我们描述了它在两条长多核苷酸链中的应用：MS2核糖核酸的A蛋白基因和φX174噬菌体的全基因组。φX174单链脱氧核糖核酸的折叠形式是一个六臂星型，其复制起点在中心位置。
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