Al-Saadi A A, Al-Samarrae S A, Altaif K I
Res Vet Sci. 1984 Mar;36(2):144-6.
This investigation was undertaken to study the immune response of Iraqi sheep vaccinated with Dictyocaulus filaria larvae (Filiraq) and to determine the effect of tetramisole on the development of resistance to reinfection. The findings confirm the effectiveness of Filiraq in conferring protection against experimental infection with D filaria. However, the administration of anthelmintic four weeks after each vaccination interfered with the development of immunity. Termination of D filaria infection at 28 days by tetramisole treatment also prevented the immune response.
本研究旨在探讨接种丝状网尾线虫幼虫疫苗（Filiraq）的伊拉克绵羊的免疫反应，并确定四咪唑对再次感染抵抗力发展的影响。研究结果证实了Filiraq在预防丝状网尾线虫实验性感染方面的有效性。然而，每次接种疫苗四周后给予驱虫药会干扰免疫力的发展。用四咪唑治疗在28天时终止丝状网尾线虫感染也会阻止免疫反应。
