Benotti J R, Grossman W
Annu Rev Med. 1984;35:113-25. doi: 10.1146/annurev.me.35.020184.000553.
Restrictive cardiomyopathy is a descriptive clinical and hemodynamic syndrome emphasizing the pathophysiologic mechanisms by which myocardial hypertrophy and/or infiltrative processes cause cardiocirculatory morbidity. This diagnosis can be made with precision only after pericardial construction is excluded and myocardial biopsy has identified the restrictive process. Though a variety of rather rare infiltrative pathological entities may be responsible for the restrictive cardiomyopathic picture, most commonly no definitive pathologic diagnosis is established despite extensive hemodynamic and histologic investigation. Nonetheless, a therapeutic trial with a calcium entry blocking agent is warranted.
限制性心肌病是一种描述性的临床和血流动力学综合征，强调心肌肥厚和/或浸润性过程导致心脏循环疾病的病理生理机制。只有在排除心包缩窄且心肌活检确定为限制性病变后，才能准确做出该诊断。尽管多种相当罕见的浸润性病理实体可能导致限制性心肌病的表现，但尽管进行了广泛的血流动力学和组织学检查，最常见的情况是仍无法确立明确的病理诊断。尽管如此，仍有必要试用钙通道阻滞剂进行治疗。
