Meaney E, Shabetai R, Bhargava V, Shearer M, Weidner C, Mangiardi L M, Smalling R, Peterson K
Am J Cardiol. 1976 Nov 4;38(5):547-56. doi: 10.1016/s0002-9149(76)80001-x.
Cardiac amyloidosis is not characterized by a single hemodynamic pattern. Some of the cases present the clinical findings of restrictive cardiomyopathy and in these differentiation from constrictive pericarditis remains difficult in spite of the introduction of techniques designed to assess myocardial contractility and ventricular diastolic compliance. The clinical features and the demonstration of left ventricular diastolic pressure greater than right remain the most useful means of distinguishing restrictive cardiomyopathy from constrictive pericarditis. In other cases of cardiac amyloidosis the diastolic pressure is elevated throughout diastole and ventricular ejectile ability is lost. These cases do not simulate constrictive pericarditis and should not be classified as restrictive cardiomyopathy.
心脏淀粉样变性并非以单一的血流动力学模式为特征。部分病例呈现限制性心肌病的临床表现，尽管引入了旨在评估心肌收缩力和心室舒张顺应性的技术，但在这些病例中，与缩窄性心包炎进行鉴别仍很困难。临床特征以及左心室舒张压高于右心室舒张压的表现仍是区分限制性心肌病与缩窄性心包炎最有用的方法。在心脏淀粉样变性的其他病例中，整个舒张期舒张压均升高，且心室射血能力丧失。这些病例并不模拟缩窄性心包炎，不应归类为限制性心肌病。
