Caraceni T A, Parati E A, Giovannini P M, Grassi M P, Scigliano G, Carella F, Müller E E
Arch Neurol. 1984 May;41(5):516-20. doi: 10.1001/archneur.1984.04050170062019.
Huntington's chorea (HC) was studied in 14 untreated patients, in six patients receiving long-term neuroleptic treatment, and in four patients after drug withdrawal. Our results showed that patients with HC may be divided into three groups, otherwise clinically indistinguishable, on the basis of growth hormone responsiveness to dopaminergic stimuli. The existence of subpopulations of patients with HC must be considered in further studies on these subjects.
对14名未经治疗的亨廷顿舞蹈病(HC)患者、6名接受长期抗精神病药物治疗的患者以及4名停药后的患者进行了研究。我们的结果显示,根据生长激素对多巴胺能刺激的反应性,HC患者可分为三组,在临床上无法区分。在对这些受试者的进一步研究中,必须考虑HC患者亚群的存在。