血影蛋白依赖性ATP酶在维持红细胞形状中的作用。
The role of spectrin-dependent ATPase in erythrocyte shape maintenance.
作者信息
Mircevová L, Viktora L, Kodícek M, Rehácková H, Simonová A
出版信息
Biomed Biochim Acta. 1983;42(11-12):S67-71.
The paper reports on the relationship between spectrin-dependent ATPase and erythrocyte shape. It can be seen from various experiments that different treatment of erythrocyte membrane which brings about alteration in activity of spectrin-dependent ATPase, also changes erythrocyte shape. We suggest that spectrin-dependent ATPase is a large actomyosin-like protein complex with some characteristics of contractile protein which, under suitable conditions, causes a physiological tension (contraction) of the membrane. Energetically rich state of spectrin-dependent ATPase seems to be responsible for this phenomenon.
该论文报道了血影蛋白依赖性ATP酶与红细胞形状之间的关系。从各种实验中可以看出，对红细胞膜进行不同处理会导致血影蛋白依赖性ATP酶活性改变，同时也会改变红细胞形状。我们认为，血影蛋白依赖性ATP酶是一种大型的肌动球蛋白样蛋白质复合物，具有一些收缩蛋白的特性，在合适的条件下，会引起膜的生理张力（收缩）。血影蛋白依赖性ATP酶的高能状态似乎是造成这种现象的原因。
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