Tobelem G
J Pharmacol. 1984;15 Suppl 1:85-94.
Interactions between platelets and blood vessels are very important to maintain the equilibrium between haemorrhagy and thrombosis. Plasmatic membrane of platelets, with its external surface rich in carbon hydrates, contains specific glycoproteins the role of which is essential in adhesive mechanisms and platelet aggregation. This cellular surface also carry numerous receptors for many agents. New progresses will allow a better physiopharmacological approach of platelet inhibition, adhesion and aggregation.