Schwartz R W, Sachatello C R, Hyde G L
South Med J. 1984 Jun;77(6):697-9, 702. doi: 10.1097/00007611-198406000-00008.
We report the successful management of two patients with abdominal wall gas gangrene and emphasize the principles of proximal gastrointestinal diversion and the initial use of 100% fraction of inspired oxygen (FiO2). Each patient lacked an abdominal wall and intractable fistulas developed. Complete diversion of their gastrointestinal tracts at a proximal level facilitated closure of the fistulas and prevented possible peritoneal contamination. One patient's arterial oxygen pressure was maintained in the 200 to 300 range for two days after admission. This level has been shown to be adequate to stop clostridial alpha toxin production.
我们报告了两例腹壁气性坏疽患者的成功治疗情况，并强调了近端胃肠道改道和初始使用100%吸入氧分数（FiO2）的原则。每位患者均存在腹壁缺损且出现了难治性瘘管。在近端水平完全改道其胃肠道有助于瘘管闭合，并防止可能的腹腔污染。一名患者入院后两天动脉氧分压维持在200至300范围内。已证明该水平足以停止梭菌α毒素的产生。
