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牙科技术人员中甲基丙烯酸甲酯的局部神经毒性。

Local neurotoxicity of methyl methacrylate among dental technicians.

作者信息

Seppäläinen A M, Rajaniemi R

出版信息

Am J Ind Med. 1984;5(6):471-7. doi: 10.1002/ajim.4700050606.

Abstract

Dental technicians often handle methyl methacrylate bare-handed before the polymerization reaction, and the monomer can penetrate the skin during the process. Nerve conduction velocities were determined in 20 dental technicians who had slight neurological complaints and in 18 healthy control persons. The motor and sensory conduction velocities in the forearm sections were normal and similar in both the study and the control group. Dental technicians had significantly slower distal sensory conduction velocities from the digits I, II and III on the right hand and also from the radial aspects of the digits II and III on the left hand than did the controls. Findings are considered to represent mild axonal degeneration on the areas with the closest and most frequent contact with methyl methacrylate.

摘要

牙科技术人员在聚合反应前常常徒手处理甲基丙烯酸甲酯,在此过程中单体可穿透皮肤。对20名有轻微神经症状的牙科技术人员和18名健康对照者测定了神经传导速度。研究组和对照组在前臂段的运动和感觉传导速度均正常且相似。与对照组相比,牙科技术人员右手示指、中指和环指以及左手示指和中指桡侧的远端感觉传导速度明显较慢。这些发现被认为代表了与甲基丙烯酸甲酯接触最密切且最频繁区域的轻度轴突退变。

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