Murphy K A, Cornish R D
Arch Phys Med Rehabil. 1984 Jun;65(6):334-7.
Forty-eight patients seeking treatment for low back pain were assessed in the acute stage to see if they exhibited characteristics that would predict response to medical treatment. It was hoped that, if there were personality and demographic differences between patients who did and those who did not respond to standard medical treatment, potential chronic pain patients could be identified and targeted for special treatment. Stepwise discriminant analysis yielded a prediction equation that correctly identified 41 of the 48 cases (85.4%). Acute patients who became chronic complained of pain over a wider area of the body; had deeper, more central pain; were highly anxious; and had a lower activity level. Although cross-validation studies are needed, identification of potentially chronic pain patients may be feasible, making appropriate early intervention possible.
对48名因腰痛寻求治疗的患者在急性期进行了评估，以确定他们是否表现出能够预测对药物治疗反应的特征。人们希望，如果对标准药物治疗有反应和无反应的患者之间存在人格和人口统计学差异，那么潜在的慢性疼痛患者就可以被识别出来并接受特殊治疗。逐步判别分析得出了一个预测方程，该方程正确识别了48例中的41例（85.4%）。转为慢性的急性患者抱怨身体疼痛部位更广；疼痛更深、更集中；高度焦虑；活动水平较低。虽然需要进行交叉验证研究，但识别潜在的慢性疼痛患者可能是可行的，从而使适当的早期干预成为可能。
