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[非冠状动脉性心脏病患者的烟酸代谢]

[Nicotinic acid metabolism in patients with non-coronarogenic heart diseases].

作者信息

Borets V M, Varnakova G M

出版信息

Vopr Pitan. 1984 Mar-Apr(2):19-22.

PMID:6234700
Abstract

To study the supply with nicotinic acid, 74 patients with rheumatic fever of varying degree and circulatory disorders, 10 patients with infectious-allergic myocarditis, 15 with tonsilogenous myocardiodystrophy were examined. Seventy normal subjects served as control. The supply with vitamin PP was evaluated from the blood content of NAD, NADP and N'-methylnicotinamide and its excretion with urine. All the patients with myocarditis and rheumatic fever demonstrated a decrease in the nicotinic acid supply which became more marked as the degree of rheumatic fever rose and circulatory failure supervened. In patients with tonsilogenous myocardiodystrophy , the disturbance of the vitamin supply was less overt.

摘要

为研究烟酸供应情况,对74例不同程度风湿热及循环系统障碍患者、10例感染性过敏性心肌炎患者、15例扁桃体源性心肌营养不良患者进行了检查。70名正常受试者作为对照。根据血液中烟酰胺腺嘌呤二核苷酸(NAD)、烟酰胺腺嘌呤二核苷酸磷酸(NADP)和N'-甲基烟酰胺的含量及其尿排泄情况评估维生素PP的供应。所有心肌炎和风湿热患者均表现出烟酸供应减少,且随着风湿热程度的加重和循环衰竭的出现,这种减少更为明显。在扁桃体源性心肌营养不良患者中,维生素供应的紊乱不太明显。

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1
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