[Regulation of hydroxylation in position 21 of steroids in adrenal cortex cells of newborn rats, in culture. Utilization of aminoglutethimide and of exogenous steroids].
作者信息
Raoux R J, Maume B F
出版信息
C R Seances Soc Biol Fil. 1984;178(1):84-91.
PMID:6234975
Abstract
The use of aminoglutethimide at 5.10(-4) mol/l, inhibitor of endogenous steroidogenesis, and of exogenous progesterone (20 micrograms/ml) as substrate allowed the control of the steroid 21-hydroxylating reaction in cultured newborn rat adrenocortical cells. This method has been employed to show that the 21-hydroxylation by these cells is strongly induced by the adrenocorticotropic hormone (20 mU/ml).
摘要
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