Berns M W, Rettenmaier M, McCullough J, Coffey J, Wile A, Berman M, DiSaia P, Weinstein G
Lasers Surg Med. 1984;4(1):73-7. doi: 10.1002/lsm.1900040110.
Systemically injected hematoporphyrin derivative (HPD) in combination with red laser light (630 nm) was used to treat a patient with intraepithelial neoplasia of the vulva. Since the patient had psoriasis in the mons pubis area this region also was exposed to the red light. The psoriasis treatment area was divided into two regions receiving 40 and 20 J/cm2. Both psoriatic zones responded vigorously to the HPD + light treatment, forming eschars by 1 week postirradiation. All three treatment zones (the neoplastic area and the two psoriatic areas) underwent normal reepithelialization by 17 days.
全身注射血卟啉衍生物(HPD)并结合红色激光(630纳米)用于治疗一名外阴上皮内瘤变患者。由于患者耻骨联合区域患有银屑病,该区域也接受了红光照射。银屑病治疗区域被分为接受40和20 J/cm²的两个区域。两个银屑病区域对HPD +光治疗反应强烈,照射后1周形成焦痂。所有三个治疗区域(肿瘤区域和两个银屑病区域)在17天时均经历了正常的上皮再形成。