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[肢端肥大症的心血管变化。前瞻性研究]

[Cardiovascular changes in acromegaly. Prospective study].

作者信息

Badui E, González C, García Rubi D, Futran J, Olguín R, Espinosa R

出版信息

Arch Inst Cardiol Mex. 1984 May-Jun;54(3):287-92.

PMID:6235787
Abstract

We present 38 acromegalyc patients who were studied by non invasive methods to assess the frequency of cardiovascular complications. Seventy one percent of the cases presented some type of cardiovascular alteration. In 68% we observed left ventricular hypertrophy by echocardiography which was the most sensitive method to detect it. In 71% we obtained abnormal electrocardiograms, mainly because of conduction disturbances, being right bundle branch block the most frequent. Half of the cases had pulmonary fibrosis and chronic bronchitis. Arterial hypertension was present in 32%. Diabetes mellitus in 21%. Only 2 cases had coronary heart disease. In 37% of the patients who underwent hypophisectomy we observed regression up to 90% of the cardiac complications except for left ventricular hypertrophy and pulmonary fibrosis. None of the patients has died.

摘要

我们报告了38例肢端肥大症患者,采用非侵入性方法对其进行研究以评估心血管并发症的发生率。71%的病例出现了某种类型的心血管改变。68%的病例经超声心动图检查发现左心室肥厚,这是检测左心室肥厚最敏感的方法。71%的病例心电图异常,主要是由于传导障碍,其中右束支传导阻滞最为常见。一半的病例有肺纤维化和慢性支气管炎。32%的患者有动脉高血压。21%的患者有糖尿病。只有2例有冠心病。在接受垂体切除术的患者中,37%的患者心脏并发症消退达90%,但左心室肥厚和肺纤维化除外。无一例患者死亡。

相似文献

1
[Cardiovascular changes in acromegaly. Prospective study].[肢端肥大症的心血管变化。前瞻性研究]
Arch Inst Cardiol Mex. 1984 May-Jun;54(3):287-92.
2
[The heart in acromegaly: an echocardiographic study].[肢端肥大症患者的心脏:一项超声心动图研究]
J Cardiogr. 1984 Oct;14(3):459-69.
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[Standard electrocardiography and Holter monitoring changes in acromegalic patients].[肢端肥大症患者的标准心电图及动态心电图监测变化]
Pol Merkur Lekarski. 2007 Jun;22(132):519-23.
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[Heart disease in acromegaly. Study of 27 patients].[肢端肥大症中的心脏病。27例患者的研究]
Med Clin (Barc). 1996 Sep 21;107(9):326-30.
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[Terminal cardiac manifestations of acromegaly].
Ann Med Interne (Paris). 1972 Apr;123(4):425-9.
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Cardiovascular pathology in acromegaly and some effects of the 90 yttrium implant in the hypophysis.
Endocrinologie. 1978 Jul-Sep;16(3):223-8.
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Acromegalic heart disease: influence of treatment of the acromegaly on the heart.
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[Cardiovascular manifestations in mixed connective tissue disease in adults].
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Left bundle branch block and cardiovascular morbidity and mortality in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention For Endpoint Reduction in Hypertension study.左束支传导阻滞与左心室肥厚高血压患者的心血管发病率和死亡率:氯沙坦干预降低高血压终点事件研究
J Hypertens. 2008 Jun;26(6):1244-9. doi: 10.1097/HJH.0b013e3282fcc23c.

引用本文的文献

1
Acromegalic cardiomyopathy. An echocardiographic study.肢端肥大症性心肌病。一项超声心动图研究。
J Endocrinol Invest. 1988 Mar;11(3):159-64. doi: 10.1007/BF03350125.