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评估特定B族维生素营养状况的更新实验室方法。

Newer laboratory methods for assessing nutriture of selected B-complex vitamins.

作者信息

Sauberlich H E

出版信息

Annu Rev Nutr. 1984;4:377-407. doi: 10.1146/annurev.nu.04.070184.002113.

DOI:10.1146/annurev.nu.04.070184.002113
PMID:6235828
Abstract

This review is limited to progress in the development of new or improved laboratory procedures to assess the nutriture of thiamin, riboflavin, niacin, vitamin B6, and folic acid. There has been marked progress in this area for the other vitamins as well. The increased availability of radioassay techniques and HPLC methodologies that have application in nutrition assessment is significant. However, for a number of the vitamins, there is still a need for additional methods that provide functionally interpretable preclinical information and give accurate assessment of body reserves of the nutrient. Often the guides used to interpret the information obtained are tentative and require validation or revision. This situation is further complicated by the frequent lack of suitable reference standards for quality controls and interlaboratory validation.

摘要

本综述仅限于评估硫胺素、核黄素、烟酸、维生素B6和叶酸营养状况的新的或改进的实验室方法的进展。其他维生素在这方面也有显著进展。可用于营养评估的放射分析技术和高效液相色谱方法的增加具有重要意义。然而,对于多种维生素来说,仍然需要其他方法来提供功能上可解释的临床前信息,并准确评估营养素的身体储备。通常用于解释所获信息的指南是暂定的,需要验证或修订。由于经常缺乏适用于质量控制和实验室间验证的参考标准,这种情况更加复杂。

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