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[一种小剂量纤溶药物(葡糖胺聚糖)在静脉炎中的应用]

[Use of a minor fibrinolytic drug (mesoglycan) in phlebitis].

作者信息

Scondotto G, De Fabritiis A, Guastarobba A, Amato A C, Filippini M

出版信息

Minerva Med. 1984 Jul 14;75(28-29):1733-8.

PMID:6236381
Abstract

33 subjects (28 women and 5 men), aged 22-72 and suffering from various types and degrees of venous pathology (varicose syndromes, post-phlebitic syndromes, recent thrombophlebitis) were subjected to clinical study. All patients were treated with Mesoglycan, a fibrinolysis stimulating drug, in oral doses of 2 12 mg capsules 3 times a day for 30 days. The study was intended to show the effectiveness of such treatment, and consisted of a clinical and instrumental assessment of the subjective and objective symptoms associated with venous conditions. The results obtained were analysed statistically and confirmed the therapeutic effectiveness of Mesoglycan for this type of pathology, particularly for thrombophlebitis where treatment produced early and lasting results. In conclusion, both the experimental findings and the clinical results obtained, confirm the view that Mesoglycan is a drug of choice for the prevention and treatment of venous pathologies.

摘要

33名受试者(28名女性和5名男性),年龄在22至72岁之间,患有各种类型和程度的静脉疾病(静脉曲张综合征、静脉炎后综合征、近期血栓性静脉炎),接受了临床研究。所有患者均接受了刺激纤溶的药物迈之灵治疗,口服剂量为每日3次,每次2 - 12毫克胶囊,持续30天。该研究旨在证明这种治疗方法的有效性,包括对与静脉疾病相关的主观和客观症状进行临床和仪器评估。对获得的结果进行了统计分析,证实了迈之灵对这类疾病的治疗效果,特别是对血栓性静脉炎,治疗产生了早期和持久的效果。总之,实验结果和临床结果均证实了迈之灵是预防和治疗静脉疾病的首选药物这一观点。

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1
[Use of a minor fibrinolytic drug (mesoglycan) in phlebitis].[一种小剂量纤溶药物(葡糖胺聚糖)在静脉炎中的应用]
Minerva Med. 1984 Jul 14;75(28-29):1733-8.
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[Mesoglycan and fibrinolysis: therapeutic activity of oral mesoglycan in venous thrombosis. A short-term clinical, biological and instrumental study].[硫酸皮肤素与纤维蛋白溶解:口服硫酸皮肤素治疗静脉血栓形成的活性。一项短期临床、生物学和仪器研究]
Minerva Med. 1986 Oct 20;77(40):1867-72.
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[Therapeutic action of oral mesoglycan in the pharmacologic treatment of the varicose syndrome and its complications].口服硫酸皮肤素在静脉曲张综合征及其并发症药物治疗中的治疗作用
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Minerva Cardioangiol. 2007 Dec;55(6):741-53.
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Quality of live as measured by the CIVQ 20. Questionnaire following oral mesoglycan treatment of patients with chronic venous disease.采用CIVQ 20问卷对慢性静脉疾病患者进行口服硫酸软骨素治疗后所测得的生活质量。
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