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[血浆置换在免疫病理所致疾病治疗中的应用]

[Plasmapheresis in the treatment of diseases caused by immunologic pathology].

作者信息

Gorodetskiĭ V M, Ryzhko V V

出版信息

Ter Arkh. 1984;56(6):19-23.

PMID:6236574
Abstract

The authors discuss the results of the use of therapeutic plasmapheresis (290 sessions) in 56 patients with immunity-mediated diseases: hemorrhagic vasculitis, Goodpasture's syndrome, multiple sclerosis, Guillain-Barre's syndrome, rheumatoid arthritis, partial red cell aplasia, etc. Demonstrate the possibilities of the attainment of positive results provided plasmapheresis is included into the complex of therapeutic measures. Discuss the indications, criteria of the efficacy, and contraindications to plasmapheresis administration. Infer that the clinical data play the decisive role in the appraisal of the plasmapheresis efficacy. Recommend that intermittent plasmapheresis be widely used for the treatment of internal diseases.

摘要

作者讨论了56例免疫介导性疾病患者使用治疗性血浆置换(290次疗程)的结果,这些疾病包括出血性血管炎、古德帕斯彻综合征、多发性硬化症、格林-巴利综合征、类风湿性关节炎、部分红细胞再生障碍等。证明了将血浆置换纳入综合治疗措施可取得积极效果的可能性。讨论了血浆置换的适应症、疗效标准和禁忌症。推断临床数据在评估血浆置换疗效中起决定性作用。建议间歇性血浆置换广泛用于内科疾病的治疗。

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