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[人心肌梗死后动脉瘤肌肉细胞中细胞质酶和肌红蛋白活性的变化]

[Changes in the activity of cytoplasmic enzymes and myoglobin in muscle cells of postinfarction aneurysm of the human myocardium].

作者信息

Avilov V V, Saprygin D B, Rabotnikov V S, Vasilidze T V

出版信息

Vopr Med Khim. 1984 May-Jun;30(3):105-8.

PMID:6236609
Abstract

Enzymatic sprectra were studied in myocytes of human heart aneurysm as compared with the muscle cells of intact myocardium. Activities of G-6-PDH and AK as well as content of myoglobin were increased. Activity of the other enzymes studied (CPK, AsAT, IDH, MDH, LDH, PPK) was unaltered. Alterations, specific only for the muscle cells, were detected using a new calculation technique--comparison of relative (based on creatine) concentrations of myoglobin and the enzymatic activities in aneurysm and intact myocardium.

摘要

与完整心肌的肌肉细胞相比,对人心室壁瘤心肌细胞中的酶谱进行了研究。发现葡萄糖-6-磷酸脱氢酶(G-6-PDH)和腺苷激酶(AK)的活性以及肌红蛋白含量增加。所研究的其他酶(肌酸磷酸激酶(CPK)、天冬氨酸转氨酶(AsAT)、异柠檬酸脱氢酶(IDH)、苹果酸脱氢酶(MDH)、乳酸脱氢酶(LDH)、丙酮酸激酶(PPK))的活性未发生改变。使用一种新的计算技术——比较瘤壁和完整心肌中肌红蛋白的相对(基于肌酸)浓度以及酶活性,检测到仅在肌肉细胞中出现的变化。

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