Harris M N, Plantevin O M, Crowther A
Br J Anaesth. 1984 Nov;56(11):1213-7. doi: 10.1093/bja/56.11.1213.
Fifty-six patients undergoing elective laparoscopy were allocated randomly to two groups. Group H received alcuronium and were ventilated artificially using 0.5% halothane and nitrous oxide in oxygen. Group E breathed spontaneously a mixture of enflurane and nitrous oxide in oxygen. Arterial pressure, heart rate, tidal volume, respiratory rate and end-tidal carbon dioxide tension (PECO2) were monitored. The electrocardiogram (ECG) was recorded continuously using magnetic tape, from before induction until the patient left the recovery area. The incidence of arrhythmias was similar in the two groups. No arrhythmias occurred after the insufflated carbon dioxide had been removed from the abdomen. Spontaneous ventilation with enflurane anaesthesia is a simple and safe, technique for routine laparoscopy, providing the intra-abdominal pressure does not exceed 25 mm Hg.