The structure and function of cholinergic synaptic vesicles. The Third Thudichum Lecture.

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作者信息

Whittaker V P

出版信息

Biochem Soc Trans. 1984 Aug;12(4):561-76. doi: 10.1042/bst0120561.

DOI:10.1042/bst0120561

PMID:6237945

Abstract

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The structure and function of cholinergic synaptic vesicles. The Third Thudichum Lecture.

Biochem Soc Trans. 1984 Aug;12(4):561-76. doi: 10.1042/bst0120561.

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Synaptic vesicles contain small ribonucleic acids (sRNAs) including transfer RNA fragments (trfRNA) and microRNAs (miRNA).突触小泡含有小核糖核酸（sRNAs），包括转运RNA片段（trfRNA）和微小核糖核酸（miRNA）。

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Individual synaptic vesicles from the electroplaque of Torpedo californica, a classic cholinergic synapse, also contain transporters for glutamate and ATP.来自电鳐（一种典型的胆碱能突触）电板的单个突触小泡也含有谷氨酸和ATP的转运体。

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Immunoisolation of GABA-specific synaptic vesicles defines a functionally distinct subset of synaptic vesicles.γ-氨基丁酸特异性突触小泡的免疫分离确定了突触小泡在功能上不同的一个亚群。

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Ouabain induces acetylcholine release from pure cholinergic synaptosomes independently of extracellular calcium concentration.哇巴因可独立于细胞外钙浓度诱导纯胆碱能突触小体释放乙酰胆碱。

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