Revazov A A, Ginter E K, Asanov A Iu, Gar'kavtseva R F, Turaeva Sh M
Genetika. 1984 Sep;20(9):1542-8.
The paper deals with demographic, genealogical and genetic characterization of one Turkmenian isolate--"Nochur". The data on its load of hereditary diseases were published previously. The Turkmenian "Nochurly" tribe consists of 19 large and small clanes. 600 nuclear families live in a small mountain valley of the same name. The share of prereproductive age class is 60%, of reproductive class--29%, this value for postreproductive class being 11%. The average number of children per family, when the families have completed their reproductive period, is 6.84. The average duration of generation (the mean parental age to the birth time of a mean newborn) is 37.7 and 31 years for a man and woman, respectively. Immigration into Nochur is practically absent, there is a flow of emigrants to the capital of the Republic, Ashkhabad. A very high level of assortative mating has been noted, the minimal estimation of inbreeding coefficient being 0.033 (the pedigree) and the maximal--0.0529 (isonimy). Diminishing of the number of lethal equivalents between 1940-1965 and 1966-1980 was discovered. This can be explained by a decrease in natural selection pressure. The data on distribution of genetic markers of the ABO, MN, Rh, Hp and Pp systems within this isolated population are presented.
本文探讨了土库曼斯坦一个隔离群体——“诺丘尔”的人口统计学、谱系学和遗传学特征。关于其遗传性疾病负荷的数据此前已发表。土库曼斯坦的“诺丘尔利”部落由19个大小氏族组成。600个核心家庭生活在一个同名的小山谷中。生殖前期年龄段的比例为60%，生殖期年龄段为29%，生殖后期年龄段为11%。当家庭完成生育期时，每个家庭的平均子女数为6.84个。一代的平均时长（平均新生儿出生时父母的平均年龄）男性为37.7岁，女性为31岁。几乎没有移民进入诺丘尔，有移民流向共和国首都阿什哈巴德。已注意到高度的选型交配，近交系数的最小估计值为0.033（系谱法），最大估计值为0.0529（同姓名法）。发现1940 - 1965年至1966 - 1980年间致死当量数量减少。这可以用自然选择压力的降低来解释。本文还呈现了该隔离群体中ABO、MN、Rh、Hp和Pp系统遗传标记的分布数据。
