Allain P, Mauras Y, Tafforeau C, Houssin A, Cartier F
Presse Med. 1984 Oct 20;13(37):2249-51.
Rubidium concentrations were measured by flame emission spectrophotometry in whole blood, plasma and red cells from male and female controls and from dialyzed and non-dialyzed patients of both sexes with chronic renal failure. Rubidium concentrations (mumol/l) in male and female controls respectively were: 2.29 +/- 0.29 and 1.96 +/- 0.46 in plasma: 36..79 +/- 5.90 and 30.19 +/- 6.11 in whole blood; 74.57 +/- 10.37 and 72.22 +/- 12.76 in erythrocytes. The red cell rubidium/plasma rubidium ratios were 32.6 in males and 38.3 in females. Compared with controls, dialyzed male and female patients showed, before dialysis, a decrease in rubidium concentrations of respectively -30% and -17% in plasma, -64% and -61% in whole blood, -40% and -33% in erythrocytes. A further decrease of 25% in rubidium plasma concentrations was observed after dialysis. Non dialyzed patients had an increase in plasma concentrations (+14% in males, +23% in females) and a decrease in erythrocyte concentrations (-16% in males, -20% in females) as compared with controls. Our data show that plasma and red cell rubidium concentrations are fairly constant and probably regulated in healthy subjects but vary considerably in patients with renal failure.
采用火焰发射分光光度法测定了男性和女性对照组以及患有慢性肾衰竭的透析和未透析患者的全血、血浆和红细胞中的铷浓度。男性和女性对照组血浆中的铷浓度（μmol/L）分别为：2.29±0.29和1.96±0.46；全血中为36.79±5.90和30.19±6.11；红细胞中为74.57±10.37和72.22±12.76。红细胞铷/血浆铷比值男性为32.6，女性为38.3。与对照组相比，透析的男性和女性患者在透析前血浆中铷浓度分别降低了-30%和-17%，全血中降低了-64%和-61%，红细胞中降低了-40%和-33%。透析后血浆铷浓度进一步降低了25%。与对照组相比，未透析患者血浆浓度升高（男性升高14%，女性升高23%），红细胞浓度降低（男性降低16%，女性降低20%）。我们的数据表明，在健康受试者中，血浆和红细胞中的铷浓度相当恒定，可能受到调节，但在肾衰竭患者中变化很大。
