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[骨多发性骨髓瘤。两阶段全身照射治疗。7例]

[Multiple myeloma of the bones. Treatment by 2-stage whole-body irradiation. 7 cases].

作者信息

Troussard X, Roussel A, Leporrier M, Loyau G

出版信息

Presse Med. 1984 Nov 17;13(41):2499-502.

PMID:6239240
Abstract

Seven patients with high tumoral burden myeloma of bones were treated by two successive hemicorporeal irradiations. This treatment was strikingly effective in providing pain relief which was durable in 3 cases. It might also have reduced the tumoral mass, since partial remission was obtained in 2 cases and lasting normalization of calcaemia in one patient with a non-excreting myeloma. Its haematological side-effects did not seem to exceed those of combined chemotherapy, and its pulmonary toxicity was reduced by using corrected doses.

摘要

7例高肿瘤负荷骨骨髓瘤患者接受了两次连续的半身照射治疗。这种治疗在缓解疼痛方面效果显著,3例患者疼痛缓解持久。它还可能缩小了肿瘤体积,因为2例患者获得了部分缓解,1例非分泌型骨髓瘤患者血钙持续正常。其血液学副作用似乎不超过联合化疗,通过调整剂量降低了肺部毒性。

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