Troussard X, Roussel A, Leporrier M, Loyau G
Presse Med. 1984 Nov 17;13(41):2499-502.
Seven patients with high tumoral burden myeloma of bones were treated by two successive hemicorporeal irradiations. This treatment was strikingly effective in providing pain relief which was durable in 3 cases. It might also have reduced the tumoral mass, since partial remission was obtained in 2 cases and lasting normalization of calcaemia in one patient with a non-excreting myeloma. Its haematological side-effects did not seem to exceed those of combined chemotherapy, and its pulmonary toxicity was reduced by using corrected doses.
7例高肿瘤负荷骨骨髓瘤患者接受了两次连续的半身照射治疗。这种治疗在缓解疼痛方面效果显著，3例患者疼痛缓解持久。它还可能缩小了肿瘤体积，因为2例患者获得了部分缓解，1例非分泌型骨髓瘤患者血钙持续正常。其血液学副作用似乎不超过联合化疗，通过调整剂量降低了肺部毒性。
