Boon J H, Kloosterman A, Breukink M
Vet Parasitol. 1984 Nov;16(3-4):261-72. doi: 10.1016/0304-4017(84)90044-x.
To investigate the parasitological, serological, clinical and growth effects of continuous graded levels of Dictyocaulus viviparus inoculations in calves an experiment was carried out with 10 groups of 5 calves each. Calves were inoculated twice a week during a period of ten weeks. The range of the doses was 10-2560 infective larvae (L3) per inoculation. The results were analysed by linear and curvilinear regression of various traits on infection level. It is concluded that: A continuous exposure of calves to L3 of D. viviparus was followed by a continuous larval excretion at all levels; Results of the ELISA technique gave a very good reflection of the level of infection; Clinical signs and weight loss were evident before the parasitological and serological results were positive; The serological parameter and the parasitological parameters were mainly linearly related to the level of infection. The clinical parameters were mainly cubically related to the level of infection.
为研究持续分级水平接种胎生网尾线虫对犊牛的寄生虫学、血清学、临床及生长影响，进行了一项实验，将犊牛分为10组，每组5头。在十周的时间里，犊牛每周接种两次。每次接种的剂量范围为10 - 2560条感染性幼虫（L3）。通过对各种性状与感染水平进行线性和曲线回归分析结果。得出以下结论：犊牛持续暴露于胎生网尾线虫L3后，各水平均出现持续的幼虫排泄；ELISA技术结果很好地反映了感染水平；在寄生虫学和血清学结果呈阳性之前，临床症状和体重减轻就已明显；血清学参数和寄生虫学参数主要与感染水平呈线性关系。临床参数主要与感染水平呈三次方关系。
