Westenskow D R, Jordan W S
Can Anaesth Soc J. 1978 Jan;25(1):18-21. doi: 10.1007/BF03006777.
Changes in whole body oxygen consumption due to bolus infusions of fentanyl and thiopentone given during "balanced anaesthesia" have been examined in 17 patients. It has been shown that fentanyl causes an average decrease in oxygen consumption of 4.9, 8.4, and 5.2 per cent at 5, 10 and 15 minutes after its infusion. Thiopentone causes an average decrease of 7.0, 8.8, and 1.9 per cent at 5, 10 and 15 minutes after infusion. It is believed that the effects of fentanyl and thiopentone on oxygen consumption are caused mainly by decreases in cerebral and myocardial oxygen consumption.
在17例患者中，研究了在“平衡麻醉”期间静脉推注芬太尼和硫喷妥钠后全身耗氧量的变化。结果表明，芬太尼输注后5、10和15分钟，耗氧量平均分别下降4.9%、8.4%和5.2%。硫喷妥钠输注后5、10和15分钟，耗氧量平均分别下降7.0%、8.8%和1.9%。据信，芬太尼和硫喷妥钠对耗氧量的影响主要是由脑和心肌耗氧量的降低引起的。
