Keogh J P, Pestronk A, Wertheimer D, Moreland R
JAMA. 1980;243(8):746-9.
An epidemic of urinary retention among workers in a polyurethane manufacturing plant was discovered in the spring of 1978. The most severely affected workers had neurogenic bladders confirmed by cystometrograms and mild sensory peripheral neuropathy. A survey of the plant disclosed increased incidence of urinary retention, muscle weakness, paresthesia, insomnia, and sexual dysfunction in exposed workers. A catalyst containing dimethylaminopropionitrile was identified as the probable causative agent, and after its removal no new cases occurred.
1978年春，一家聚氨酯制造工厂的工人中发现了尿潴留疫情。受影响最严重的工人经膀胱测压证实患有神经源性膀胱，并伴有轻度感觉性周围神经病变。对该工厂的一项调查显示，接触过的工人中尿潴留、肌肉无力、感觉异常、失眠和性功能障碍的发病率有所增加。一种含有二甲基氨基丙腈的催化剂被确定为可能的致病因素，将其去除后未出现新病例。
