Petrelli F, Coderoni S, Moretti P, Marsili G, Paparelli M
Experientia. 1978 Feb 15;34(2):193-5. doi: 10.1007/BF01944672.
Biotin administration to old rats (28 months) causes in the blood an increase of ATP, glucose, triglycerides, alkaline phosphatase and a decrease of cholesterol and acid phosphatase; in the liver DNA and electrostatic interactions between DNA and histones are increased. Such parameters come within the values shown by adult rats.
给老年大鼠(28个月)施用生物素会导致血液中三磷酸腺苷、葡萄糖、甘油三酯和碱性磷酸酶增加,胆固醇和酸性磷酸酶减少;肝脏中的DNA以及DNA与组蛋白之间的静电相互作用增加。这些参数处于成年大鼠所示的值范围内。