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骨骼肌的集总式和群体随机模型:影响与预测

Lumped and population stochastic models of skeletal muscle: implications and predictions.

作者信息

Christakos C N, Lal S

出版信息

Biol Cybern. 1980;36(2):73-85. doi: 10.1007/BF00361076.

DOI:10.1007/BF00361076
PMID:6243499
Abstract

Lumped models of skeletal muscle have been assumed a) in the design of experiments and the interpretation of experimental findings, b) in theoretical studies. In this paper, a population model that takes into account the differing properties and separate (independent) activation of motor units is presented as the most appropriate for muscle. A realistic (for muscle) transformation, population leads to lumped model, resulting in the lumping of motor unit neural signals or system responses, is proposed. On this basis, the possibility of modelling muscle as a single system is examined; and the consequences of treating muscle as a lumped system, in experiments or theoretical studies, are discussed. Also, the advantages of lumping, in models of muscle, are reviewed. Predictions of a computer population model, together with actual recordings from a hand muscle, are used to confirm the results of the analysis.

摘要

在以下方面已假定采用骨骼肌集总模型

a) 实验设计及实验结果解释;b) 理论研究。本文提出一种考虑运动单位不同特性及独立激活的群体模型,认为它最适合用于肌肉研究。提出一种符合实际(针对肌肉)的转换方法,从群体模型导出集总模型,从而实现运动单位神经信号或系统响应的集总。在此基础上,研究了将肌肉建模为单一系统的可能性;并讨论了在实验或理论研究中将肌肉视为集总系统的后果。此外,还回顾了肌肉模型中集总的优点。利用计算机群体模型的预测结果以及手部肌肉的实际记录来证实分析结果。

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Lumped and population stochastic models of skeletal muscle: implications and predictions.骨骼肌的集总式和群体随机模型:影响与预测
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A study of the muscle force waveform using a population stochastic model of skeletal muscle.一项使用骨骼肌群体随机模型对肌肉力量波形的研究。
Biol Cybern. 1982;44(2):91-106. doi: 10.1007/BF00317969.
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The effects of length and stimulus rate on tension in the isometric cat soleus muscle.长度和刺激频率对猫比目鱼肌等长收缩张力的影响。
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Statistical analysis of motor unit firing patterns in a human skeletal muscle.人体骨骼肌运动单位放电模式的统计分析。
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Stochastic properties of individual motor unit interspike intervals.单个运动单位峰间间隔的随机特性。
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