Katz R J
Drug Alcohol Depend. 1980 Feb;5(2):129-33. doi: 10.1016/0376-8716(80)90189-1.
Male Sprague-Dawley rats ranging in age from 20 to 110 days were injected with two doses of morphine sulphate, and examined for behavioral activation and catalepsy. Behavioral activation increased with age, while sensitivity to catalepsy declined. Ontogenetic and pharmacological responses suggest possible separate mediation of activation and catalepsy.
选用年龄在20至110天之间的雄性斯普拉格-道利大鼠，给它们注射两剂硫酸吗啡，并检测其行为激活和僵住症情况。行为激活随年龄增长而增加，而对僵住症的敏感性则下降。个体发育和药理学反应表明，激活和僵住症可能由不同机制介导。
