β-肾上腺素能受体刺激与8-溴环磷酸腺苷对哺乳动物心肌钾外流的相反作用。
Opposite effects of beta-adrenoceptor stimulation and 8-bromo-cyclic AMP on potassium efflux in mammalian heart muscle.
作者信息
Nawrath H, Blei I, Gegner R
出版信息
Experientia. 1980 Jan 15;36(1):72-4. doi: 10.1007/BF02003981.
PMID:6244175
Abstract
beta-adrenoceptor stimulation by isoprenaline increases the potassium efflux in beating guinea-pig atria. This effect is not mimicked by 8-bromo-cyclic AMP, a cyclic AMP analogue which exerts a positive inotropic effect in this preparation.
摘要
异丙肾上腺素对β-肾上腺素能受体的刺激会增加豚鼠跳动心房中的钾外流。8-溴环磷酸腺苷（一种在该实验制剂中发挥正性肌力作用的环磷酸腺苷类似物）并不会模拟这种效应。
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