Sheĭnina L I, Kutivadze D A
Arkh Patol. 1980;42(2):35-8.
It has been concluded from the studies on the activity and location of ATPase and 5-nucleotidase in mammary and gastric tumours that some neoplasms of the mammary gland and stomach showing a high ATPase activity are histochemically related, in the former case, to the lobular myoepithelium and in the latter case, to non-differentiated cells of gastric glands which acquired a capacity for intestinal metaplasia and preserved it in the course of malignant transformation. No essential changes have been recorded in the activity of 5-nucleotidase, depending on the tumour histologic structure and degree of its maturity.
通过对乳腺和胃肿瘤中ATP酶和5 - 核苷酸酶的活性及定位研究得出结论,一些乳腺和胃的肿瘤显示出高ATP酶活性,从组织化学角度来看,前者与小叶肌上皮有关,后者与胃腺的未分化细胞有关,这些未分化细胞获得了肠化生能力并在恶性转化过程中得以保留。未发现5 - 核苷酸酶的活性根据肿瘤组织结构及其成熟程度有本质变化。