人血管内皮下层中与因子VIII相关抗原的定位
Localization of factor-VIII-related antigen in human vascular subendothelium.
作者信息
Rand J H, Sussman I I, Gordon R E, Chu S V, Solomon V
出版信息
Blood. 1980 May;55(5):752-6.
PMID:6244867
Abstract
Factor-VIII-related antigen has previously been shown to be synthesized by vascular endothelial cells. Using both an immunofluorescent staining technique and electron microscopy, we have demonstrated the presence of factor-VIII-related antigen in human vascular subendothelium. This finding may have implications in the mechanism of platelet adhesion to deendothelialized blood vessel surfaces.
摘要
此前已证明，血管内皮细胞可合成与凝血因子VIII相关的抗原。通过免疫荧光染色技术和电子显微镜，我们证实了人血管内皮下存在与凝血因子VIII相关的抗原。这一发现可能对血小板黏附于去内皮化血管表面的机制具有重要意义。
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