• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

长期给予 Δ9-四氢大麻酚与定时诱导攻击行为

Chronic delta 9-tetrahydrocannabinol administration and schedule-induced aggression.

作者信息

Cherek D R, Thompson T, Kelly T

出版信息

Pharmacol Biochem Behav. 1980 Feb;12(2):305-9. doi: 10.1016/0091-3057(80)90374-3.

DOI:10.1016/0091-3057(80)90374-3
PMID:6246545
Abstract

The effects of 0.5 mg/kg and 1.0 mg/kg of delta 9-tetrahydrocannabinol (delta 9-THC) on key-pecking maintained by a response-initiated fixed interval (FI) schedule of food presentation and schedule-induced aggression in the pigeon were studied. Initially, following the administration of delta 9-THC both the rate of key-pecking and attack responding were markedly reduced. Over sessions, tolerance developed to the suppressant effect on key-pecking, with the rate returning to the predrug level. The suppressing effect of delta 9-THC on the rate of attack remained at or near zero throughout the series of delta 9-THC injections.

摘要

研究了0.5毫克/千克和1.0毫克/千克的δ9-四氢大麻酚(δ9-THC)对鸽子通过反应启动的固定间隔(FI)食物呈现时间表维持的啄键行为以及时间表诱导的攻击行为的影响。最初,给予δ9-THC后,啄键率和攻击反应率均显著降低。随着实验阶段的进行,对啄键抑制作用产生了耐受性,啄键率恢复到用药前水平。在整个δ9-THC注射系列中,δ9-THC对攻击率的抑制作用保持在或接近零。

相似文献

1
Chronic delta 9-tetrahydrocannabinol administration and schedule-induced aggression.长期给予 Δ9-四氢大麻酚与定时诱导攻击行为
Pharmacol Biochem Behav. 1980 Feb;12(2):305-9. doi: 10.1016/0091-3057(80)90374-3.
2
Effects of chronic delta 9-tetrahydrocannabinol administration on schedule-controlled behavior of pigeons: cross-tolerance to pentobarbital and barbital.长期给予δ9-四氢大麻酚对鸽子按程序控制行为的影响:对戊巴比妥和巴比妥的交叉耐受性。
Psychopharmacology (Berl). 1981;75(1):1-4. doi: 10.1007/BF00433491.
3
Effects of delta-9-THC and a water soluble ester of delta-9-THC on schedule-controlled behavior.
Pharmacol Biochem Behav. 1975 Jan-Feb;3(1):29-32. doi: 10.1016/0091-3057(75)90077-5.
4
Effects of 1 -tetrahydrocannabinol and food deprivation level on responding maintained by the opportunity to attack.1-四氢大麻酚和食物剥夺水平对因攻击机会而维持的反应的影响。
Physiol Behav. 1972 Nov-Dec;9(5):795-800. doi: 10.1016/0031-9384(72)90054-6.
5
Failure of acute and chronic administration of delta 9-tetrahydrocannabinol to affect the repeated acquisition of serial position response in pigeons.
Pavlov J Biol Sci. 1988 Apr-Jun;23(2):57-66. doi: 10.1007/BF02995656.
6
The role of reinforcement loss in tolerance to chronic delta9-tetrahydrocannabinol effects on operant behavior of rhesus monkeys.强化损失在恒河猴对慢性 Δ9-四氢大麻酚对操作性行为影响的耐受性中的作用。
Pharmacol Biochem Behav. 1976 Aug;5(2):123-8. doi: 10.1016/0091-3057(76)90026-5.
7
Tolerance to the disruptive effects of Delta(9)-THC on learning in rats.大鼠对Δ⁹-四氢大麻酚干扰学习作用的耐受性。
Pharmacol Biochem Behav. 2002 Dec;74(1):129-40. doi: 10.1016/s0091-3057(02)00966-8.
8
Delta 9-tetrahydrocannabinol interactions with phencyclidine and ethanol: effects on accuracy and rate of responding.9-四氢大麻酚与苯环利定和乙醇的相互作用:对反应准确性和速率的影响。
Pharmacol Biochem Behav. 1992 Sep;43(1):61-70. doi: 10.1016/0091-3057(92)90639-w.
9
The effects of delta 9-tetrahydrocannabinol alone and in combination with cannabidiol on fixed-interval performance in rhesus monkeys.9-四氢大麻酚单独及与大麻二酚联合应用对恒河猴固定间隔行为表现的影响。
Psychopharmacology (Berl). 1980;72(1):21-6. doi: 10.1007/BF00433803.
10
The opioid antagonist naltrexone reduces the reinforcing effects of Delta 9 tetrahydrocannabinol (THC) in squirrel monkeys.阿片类拮抗剂纳曲酮可降低松鼠猴体内9-四氢大麻酚(THC)的强化作用。
Psychopharmacology (Berl). 2004 Apr;173(1-2):186-94. doi: 10.1007/s00213-003-1693-6. Epub 2003 Dec 11.

引用本文的文献

1
"Weeding out" violence? Translational perspectives on the neuropsychobiological links between cannabis and aggression.“根除”暴力?关于大麻与攻击性之间神经心理生物学联系的转化观点。
Aggress Violent Behav. 2024 Sep-Oct;78. doi: 10.1016/j.avb.2024.101948. Epub 2024 Apr 19.
2
The Endocannabinoid System, Aggression, and the Violence of Synthetic Cannabinoid Use, Borderline Personality Disorder, Antisocial Personality Disorder, and Other Psychiatric Disorders.内源性大麻素系统、攻击性以及合成大麻素使用、边缘性人格障碍、反社会人格障碍和其他精神障碍所致的暴力行为
Front Behav Neurosci. 2018 Mar 27;12:41. doi: 10.3389/fnbeh.2018.00041. eCollection 2018.
3
Altered affective response in marijuana smokers: an FMRI study.
大麻吸食者情感反应的改变:一项功能磁共振成像研究。
Drug Alcohol Depend. 2009 Nov 1;105(1-2):139-53. doi: 10.1016/j.drugalcdep.2009.06.019. Epub 2009 Aug 4.