Loison F, Patri B
Sem Hop. 1980;56(13-14):691-5.
A review of the literature about angio-immunoblastic lymphadenopathy since 1972 Flandrin's first description, attempts to define the main clinical, biological characteristics and clinical course of this disease. Clinically adenopathy, fever, weight loss, often hepatosplenomegaly of the appear as being constant. Hemolytic anemia and polyclonal hyperglobulinemia are the most common biological signs of this immunological disorder. In despite of spontaneous remissions, prognosis is severe. Infections complications are common and often fatal. Transformation in immunoblastic sarcoma is possible.
自1972年弗朗德兰首次描述血管免疫母细胞性淋巴结病以来的文献综述，试图明确该疾病的主要临床、生物学特征及临床病程。临床上，淋巴结病、发热、体重减轻以及常出现的肝脾肿大似乎是持续存在的症状。溶血性贫血和多克隆高球蛋白血症是这种免疫紊乱最常见的生物学体征。尽管有自发缓解情况，但预后严重。感染并发症常见且往往致命。有可能转化为免疫母细胞肉瘤。
