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缺氧应激后小鼠脑灰被的定量光镜研究。

A quantitative light microscopic study of the indusium griseum of the mouse brain following hypoxic stress.

作者信息

Sturrock R R

出版信息

J Anat. 1978 Feb;125(Pt 2):371-5.

PMID:624683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1235604/
Abstract

A quantitative study of the indusium griseum was carried out in control mice and in mice subjected to hypoxia at 390 mmHg for 2 days. One group of mice subjected to hypoxia was killed immediately after hypoxia while another group was allowed to recover for 1 week. There was no significant variation in the number of neurons in any of the groups. Neuroglia decreased from a mean number of 1741 +/- 120 in the control animals to 1251 +/- 67 in the hypoxic group and 1223 +/- 51 in the recovery group. It is postulated that this fall occurs mainly in astrocytes because these cells appear to be especially susceptible to the effects of hypoxia.

摘要

对对照组小鼠以及在390 mmHg低氧环境下暴露2天的小鼠进行了海马灰被的定量研究。一组低氧小鼠在低氧后立即处死,另一组则让其恢复1周。所有组的神经元数量均无显著差异。神经胶质细胞数量从对照组动物的平均1741±120个减少到低氧组的1251±67个和恢复组的1223±51个。据推测,这种减少主要发生在星形胶质细胞,因为这些细胞似乎对低氧影响特别敏感。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cff7/1235604/8152350bdf72/janat00360-0158-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cff7/1235604/8152350bdf72/janat00360-0158-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cff7/1235604/8152350bdf72/janat00360-0158-a.jpg

相似文献

1
A quantitative light microscopic study of the indusium griseum of the mouse brain following hypoxic stress.缺氧应激后小鼠脑灰被的定量光镜研究。
J Anat. 1978 Feb;125(Pt 2):371-5.
2
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J Gerontol. 1977 Nov;32(6):647-58. doi: 10.1093/geronj/32.6.647.
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Development of the indusium griseum. III. An autoradiographic study of cell production.灰被的发育。III. 细胞产生的放射自显影研究。
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Neuropathol Appl Neurobiol. 1980 Jan-Feb;6(1):51-68. doi: 10.1111/j.1365-2990.1980.tb00204.x.
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本文引用的文献

1
Ultrastructure of the central nervous system after prolonged hypoxia. II. Neuroglia and blood vessels.
Acta Neuropathol. 1972;22(3):235-44. doi: 10.1007/BF00684526.
2
Ultrastructure of the central nervous system after prolonged hypoxia. I. Neuronal alterations.
Acta Neuropathol. 1972;22(3):222-34. doi: 10.1007/BF00684525.
3
Investigation of glial cells in semithin sections. I. Identification of glial cells in the brain of young rats.半薄切片中神经胶质细胞的研究。I. 幼鼠大脑中神经胶质细胞的鉴定。
J Comp Neurol. 1973 May 1;149(1):43-71. doi: 10.1002/cne.901490104.
4
Quantitative changes in neuroglia in the white matter of the mouse brain following hypoxic stress.缺氧应激后小鼠脑白质中神经胶质细胞的定量变化。
J Anat. 1976 Feb;121(Pt 1):7-13.
5
Changes in the total number of neuroglia, mitotic cells and necrotic cells in the anterior limb of the mouse anterior commissure following hypoxic stress.缺氧应激后小鼠前连合前肢中神经胶质细胞、有丝分裂细胞和坏死细胞总数的变化。
J Anat. 1976 Nov;122(Pt 2):447-53.
6
A quantitative study of myelination following hypoxic stress.缺氧应激后髓鞘形成的定量研究。
J Anat. 1977 Sep;124(Pt 1):41-4.