酒精对异丙肾上腺素刺激大鼠腮腺中环状AMP积累的增强作用。
Alcohol potentiation of isoproterenol-stimulated cyclic AMP accumulation in rat parotid.
作者信息
Harper J F, Brooker G
出版信息
J Cyclic Nucleotide Res. 1980;6(1):51-62.
PMID:6247374
Abstract
The ability of beta-adrenergic agonists to elevate rat parotid cyclic AMP concentrations is potentiated greatly by certain organic solvents. Propanol was found to be more effective than other tested solvents. Propanol stimulated adenylate cyclase and inhibited low Km cyclic AMP phosphodiesterase activities however the magnitude of effect upon these enzyme activities probably does not account for the potentiation of cyclic AMP accumulation observed in intact cells.
摘要
β-肾上腺素能激动剂提高大鼠腮腺环磷酸腺苷（cAMP）浓度的能力会被某些有机溶剂大大增强。已发现丙醇比其他测试溶剂更有效。丙醇刺激腺苷酸环化酶并抑制低Km环磷酸腺苷磷酸二酯酶的活性，然而，对这些酶活性的影响程度可能无法解释在完整细胞中观察到的环磷酸腺苷积累的增强现象。
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Alcohol potentiation of isoproterenol-stimulated cyclic AMP accumulation in rat parotid.酒精对异丙肾上腺素刺激大鼠腮腺中环状AMP积累的增强作用。
J Cyclic Nucleotide Res. 1980;6(1):51-62.
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