与慢性和复发性感染状态相关的中性粒细胞功能障碍。

Neutrophil dysfunction associated with states of chronic and recurrent infection.

作者信息

Baehner R L

出版信息

Pediatr Clin North Am. 1980 May;27(2):377-401. doi: 10.1016/s0031-3955(16)33857-3.

Abstract

Infants, children, and young adults who suffer chronic and recurrent bacterial or fungal infection despite adequate numbers of circulating granulocytes and normal or elevated levels of immunoglobulins should be suspected of having fundamental defects in granulocyte functioning. This article considers clinical disorders for which there is evidence for associated defects of polymorphonuclear leukocytes.

摘要

尽管循环粒细胞数量充足且免疫球蛋白水平正常或升高，但仍患有慢性复发性细菌或真菌感染的婴儿、儿童和年轻人，应怀疑其粒细胞功能存在根本性缺陷。本文探讨了有证据表明存在多形核白细胞相关缺陷的临床病症。