Suzuki Y, Sugihara M, Matsuyama S, Tomoda H
Radioisotopes. 1980 Feb;29(2):73-8. doi: 10.3769/radioisotopes.29.2_73.
Myocardial scintigrams with 99mTc-pyrophosphate (PYP) were performed in 30 patients with acute myocardial infarct (AMI) and positive scintigrams were obtained in the 24 patients. In 12 patients the size of the AMI estimated from the scintigram with 99mTc-PYP was compared with the pulmonary capillary wedge pressure (PCWP). In the 7 patients with PCWP below 10 mmHg the mean area of the AMIs was 22 +/- 5.5 cm2 and that of in the 5 patients with PCWP beyond 10 mmHg was 41 +/- 12.4 cm2. This difference was statistically significant (p less than 0.05). In comparison with chest X-ray findings, the average size of the AMIs among 6 patients with alveolar and/or interstitial edema was 43 +/- 11.9 cm2 and that of among 8 patients without pulmonary edema was 25 +/- 9 cm2. The left ventricular ejection fraction (LVEF) was obtained by first pass method. In 12 patients LVEF and PCWP was compared. The 7 patients with PCWP below 10 mmHg did show significantly larger LVEF (49 +/- 8.2%) than that of 5 patients with PCWP beyond 10 mmHg (33 +/- 6.1%) (p less than 0.01). The mean LVEF in the 7 patients with pulmonary edema was 35 +/- 10.2% and that of in the 8 patients without pulmonary was 48 +/- 5.3%. Myocardial scintigram and radionuclide angiocardiography with 99mTc-PYP were useful for evaluation of the left ventricular function as well as detection of the AMI.
对30例急性心肌梗死（AMI）患者进行了99mTc-焦磷酸盐（PYP）心肌闪烁扫描，其中24例扫描结果为阳性。对12例患者，将根据99mTc-PYP闪烁扫描估算的AMI面积与肺毛细血管楔压（PCWP）进行比较。在PCWP低于10mmHg的7例患者中，AMI的平均面积为22±5.5平方厘米，而在PCWP高于10mmHg的5例患者中，AMI的平均面积为41±12.4平方厘米。这种差异具有统计学意义（p<0.05）。与胸部X线检查结果相比，6例有肺泡和/或间质水肿患者的AMI平均面积为43±11.9平方厘米，8例无肺水肿患者的AMI平均面积为25±9平方厘米。左心室射血分数（LVEF）通过首次通过法获得。对12例患者比较了LVEF和PCWP。PCWP低于10mmHg的7例患者的LVEF（49±8.2%）显著高于PCWP高于10mmHg的5例患者（33±6.1%）（p<0.01）。7例有肺水肿患者的平均LVEF为35±10.2%，8例无肺水肿患者的平均LVEF为48±5.3%。99mTc-PYP心肌闪烁扫描和放射性核素心血管造影对评估左心室功能以及检测AMI很有用。
