[Evaluation of the left ventricular function by myocardial scintigram and radionuclide angiocardiography with technetium-99m pyrophosphate in patients with acute myocardial infarct (author's transl)].

Myocardial scintigrams with 99mTc-pyrophosphate (PYP) were performed in 30 patients with acute myocardial infarct (AMI) and positive scintigrams were obtained in the 24 patients. In 12 patients the size of the AMI estimated from the scintigram with 99mTc-PYP was compared with the pulmonary capillary wedge pressure (PCWP). In the 7 patients with PCWP below 10 mmHg the mean area of the AMIs was 22 +/- 5.5 cm2 and that of in the 5 patients with PCWP beyond 10 mmHg was 41 +/- 12.4 cm2. This difference was statistically significant (p less than 0.05). In comparison with chest X-ray findings, the average size of the AMIs among 6 patients with alveolar and/or interstitial edema was 43 +/- 11.9 cm2 and that of among 8 patients without pulmonary edema was 25 +/- 9 cm2. The left ventricular ejection fraction (LVEF) was obtained by first pass method. In 12 patients LVEF and PCWP was compared. The 7 patients with PCWP below 10 mmHg did show significantly larger LVEF (49 +/- 8.2%) than that of 5 patients with PCWP beyond 10 mmHg (33 +/- 6.1%) (p less than 0.01). The mean LVEF in the 7 patients with pulmonary edema was 35 +/- 10.2% and that of in the 8 patients without pulmonary was 48 +/- 5.3%. Myocardial scintigram and radionuclide angiocardiography with 99mTc-PYP were useful for evaluation of the left ventricular function as well as detection of the AMI.