Leonova G N, Isachkova L M, Baranov N I, Krugliak S P
Vopr Virusol. 1980 Mar-Apr(2):173-6.
Composite studies conducted annually in the Primorsky kray showed the tick-borne encephalitis virus to play the main etiological role in the group of encephalites with the spring-summer incidence. In 1976--1978, virological studies of 69 cases of the disease yielded 11 strains of tick-borne encephalitis virus. In 1978, from the blood of clinically normal woman after a tick bite strain 555 was first isolated which was identified as Powassan virus, and antigenemia was observed for 53 days using the fluorescent antibody technique. In the same period, serological examinations of the blood sera from 117 patients demonstrated antibody to tick-borne encephalitis virus in 69.2%, to Powassan virus in 4,3% and to both viruses simultaneously in 4.3%. Besides, antibody to tick-borne encephalitis virus, Powassan virus and both viruses simultaneously was found in patients with progredient forms of tick-borne encephalitis and in subjects with the history of tick attachment.
滨海边疆区每年进行的综合研究表明,蜱传脑炎病毒在春夏季发病的脑炎组中起主要病因作用。1976 - 1978年,对69例该病进行病毒学研究,分离出11株蜱传脑炎病毒。1978年,首次从一名被蜱叮咬后临床正常的女性血液中分离出555株病毒,经鉴定为波瓦桑病毒,并采用荧光抗体技术观察到53天的抗原血症。同期,对117例患者血清进行血清学检查,结果显示,69.2%的患者对蜱传脑炎病毒呈抗体阳性,4.3%的患者对波瓦桑病毒呈抗体阳性,4.3%的患者对两种病毒均呈抗体阳性。此外,在蜱传脑炎进行性形式的患者和有蜱附着史的受试者中发现了对蜱传脑炎病毒、波瓦桑病毒以及两种病毒均呈抗体阳性的情况。