Glant T, Hadházy C, Csernyánszky H
Acta Biol Acad Sci Hung. 1975;26(3-4):197-208.
Collagen-free extracts were prepared from bovine, porcine and canine hyaline, elastic and fibrous cartilages, articular capsule, tendon, aorta, cortical bone and regenerating articular surfaces. The extracts were investigated with antisera to bovine nasal septal cartilage, dog articular cartilage and non-collagenous protein fraction of bovine cortical bone. Immunodiffusion, immunoelectrophoresis, and immunohistochemical methods were used. In the different supporting tissues of the three animal species a common antigen, probably of proteoglycan origin, was demonstrated. The finer differences in antigenicity between the different tissues are probably due to the variations in proteoglycan composition of the given supporting tissues. Owing to the wide-spread occurrence of the antigen, the authors suggest the term "species-common connective tissue antigen" instead of the "species-common cartilage antigen" used so far.
从牛、猪和犬的透明软骨、弹性软骨和纤维软骨、关节囊、肌腱、主动脉、皮质骨以及再生关节表面制备了无胶原蛋白提取物。用抗牛鼻中隔软骨、犬关节软骨和牛皮质骨非胶原蛋白部分的抗血清对提取物进行研究。采用了免疫扩散、免疫电泳和免疫组织化学方法。在这三种动物的不同支持组织中，证实了一种可能起源于蛋白聚糖的共同抗原。不同组织之间抗原性的细微差异可能是由于特定支持组织中蛋白聚糖组成的变化。由于该抗原广泛存在，作者建议用“种属共同结缔组织抗原”一词取代迄今使用的“种属共同软骨抗原”。
