Boer K, Nolten J W
J Endocrinol. 1978 Jan;76(1):155-63. doi: 10.1677/joe.0.0760155.
The spike activity of 191 antidromically identified paraventricular units was recorded during labour and the oestrous cycle of rats under urethane anaesthesia. Accelerated bursts of neuronal activity, as reported to occur during suckling, were not observed and changes in firing rate were not correlated with individual uterine contractions. There was, however, an increase in the magnitude of the mean spontaneous firing rate of antidromically identified neurosecretory cells during labour, as compared with all stages of the oestrous cycle. This increase was mainly caused by (1) a marked reduction (greater than 25%) in the percentage of totally silent cells and (2) an increase in the magnitude of the mean firing rate of the phasically firing units (1.58-3.44 spikes/s). It was concluded from these increases in spike activity that the tonic release of neurohypophysial hormones is stimulated during labour, and that this may contribute to the induction and course of labour.
在乌拉坦麻醉下，记录了191个经逆向鉴定的室旁核单位在大鼠分娩和发情周期中的锋电位活动。未观察到如哺乳期间所报道的神经元活动加速爆发，且放电频率的变化与个体子宫收缩无关。然而，与发情周期的所有阶段相比，分娩期间经逆向鉴定的神经分泌细胞的平均自发放电频率幅度有所增加。这种增加主要是由以下原因引起的：（1）完全沉默细胞的百分比显著降低（超过25%）；（2）相位性放电单位的平均放电频率幅度增加（1.58 - 3.44次/秒）。从这些锋电位活动的增加得出结论，分娩期间神经垂体激素的紧张性释放受到刺激，这可能有助于分娩的诱导和进程。
